TABLE 1

Summary of Main Properties of 8 PVE Correction Approaches^*

Property	RC	GTM	Deconvolution	Partition based	Multiresolution	Fitting	Anatomic maximum a posteriori	Kinetic modeling
Assumes tumor is spheric?	No	No	No	No	No	Yes	No	No
Assumes known tumor volume?	Yes	Yes	No	Yes	No	Yes	Yes	No
Assumes uniform tumor uptake?	Yes	Yes	Not necessarily	Yes	No	Yes	No	No
Assumption(s) regarding tissues surrounding tumor	Locally uniform, known uptake	Piecewise constant, unknown uptake	No	Piecewise constant, known uptake	Gray levels correlated with those of anatomic data	Locally uniform, unknown uptake	Partially known	No
Needs anatomic data?	Not necessarily	Yes, registered	No	Yes, registered	Yes, registered	No	Yes	Not necessarily
Mode of action	After reconstruction	After reconstruction	After reconstruction	After reconstruction	After reconstruction	After reconstruction	During reconstruction	After reconstruction, time series required
Type of results	Tumor uptake value	Tumor average uptake value	Tumor average uptake value	Image of tumor compartment	PVE-corrected image	Tumor average uptake value	PVE-corrected image	Kinetic parameters compensated for PVE
Reference(s) for PET tumor imaging	7,17,18,22,23,50,51,53,54		30		37	38		47,50