TABLE 2

Mean Volumes and Glucose Metabolism of Each Region

Absolute volume (cm3)
GroupTIVWBHippOccStr
DLB1,477 ± 140925 ± 1061.95 ± 0.3495.4 ± 12.38.96 ± 2.16*
AD1,393 ± 103*847 ± 75*1.60 ± 0.48*85.3 ± 8.59.90 ± 1.49
NC1,553 ± 285958 ± 1902.18 ± 0.5495.7 ± 18.111.53 ± 4.92
Relative volume
GroupWB/TIVHipp/TIVOcc/TIVStr/TIV
DLB62.5 ± 0.0240.132 ± 0.0186.45 ± 0.380.602 ± 0.115†
AD60.9 ± 0.040.115 ± 0.034*6.13 ± 0.540.712 ± 0.109
NC61.7 ± 0.0430.140 ± 0.0246.17 ± 0.510.723 ± 0.155
Relative glucose metabolism normalized to pontine metabolism
GroupHipp/ponsOcc/ponsStr/pons
DLB0.972 ± 0.1120.853 ± 0.075‡1.121 ± 0.129
AD0.856 ± 0.124§0.978 ± 0.1471.136 ± 0.099
NC0.982 ± 0.991.045 ± 0.1051.184 ± 0.104
Relative glucose metabolism normalized to sensorimotor metabolism
GroupHipp/SMOcc/SMStr/SM
DLB0.914 ± 0.0831.011 ± 0.065‡1.054 ± 0.097
AD0.803 ± 0.093§1.105 ± 0.0771.069 ± 0.099
NC0.854 ± 0.0751.096 ± 0.1131.032 ± 0.106

  • ↵* Significantly smaller than NC (P < 0.05).

  • ↵† Significantly smaller than NC and AD (P < 0.05).

  • ↵‡ Significantly lower than NC and AD (P < 0.05).

  • ↵§ Significantly lower than NC and DLB (P < 0.05).

  • WB = whole brain.

  • Hipp and Str values are shown as average of right and left values.