TABLE 1

BP Values in Dorsal Striatum and Midbrain for 3 Sets of Images for Age-Paired Subjects

	BP value (mean ± SD)			% increase in BP value: native HRRT/HR+	Average ROI volume (mm³)
Dopaminergic region	HR+	Native HRRT	Smoothed HRRT	% increase in BP value: native HRRT/HR+	Average ROI volume (mm³)
Dorsal striatum	6.8 ± 1.2	8.9 ± 1.1^*^†	7.5 ± 0.7	+32.3	12,590 ± 1,465
Dorsal caudate	6.3 ± 0.9	8.1 ± 1.4^*^†	6.9 ± 1.0	+29.2	6,816 ± 971
Dorsal putamen	7.2 ± 1.1	9.7 ± 1.2^*^†	8.2 ± 0.8	+35.1	5,774 ± 854
Midbrain	1.1 ± 0.3	2.2 ± 0.1^*	1.0 ± 0.3	+92.4	830

↵* P < 0.005 statistically different from HR+ images (Mann–Whitney U test).
↵† P < 0.05 statistically different from smoothed HRRT images (Wilcoxon rank test).
Volume of anatomic ROIs in cerebellum and striatum (mean ± SD) as well as volume of standardized ROIs in midbrain are expressed in mm³.