TABLE 1

Clinical Characteristics, Results of 99mTc-IL-8 Scintigraphy, Verification Procedures, and Final Diagnoses for 20 Patients with Various Suspected Infectious Foci

Patient (sex/age [y])Suspected focus99mTc-IL-8 scintigraphy resultsVerificationFinal diagnosisFollow-up (mo)
1 (F/53)Pelvic abscess with fistula+ (TP)C (Pseudomonas aeruginosa)Pelvic abscess with fistula3
2 (M/61)Caval filter− (TN)R, FUCaval filter not infected18
3 (M/76)Knee prosthesis+ (TP)S, H (chronic inflammation and osteomyelitisInfected knee prosthesis12
4 (M/66)Vertebral osteomyelitis− (FN)S, C (Escherichia coli)Vertebral osteomyelitis3
5 (M/31)Humerus+ (TP)C (Staphylococcus epidermidis)Osteomyelitis of shoulder11
6 (M/74)Ankle− (TN)H (leukocytoclastic vasculitis), FUVasculitis, no infection6
7 (M/21)Liver+ (TP)C (Staphylococcus aureus), SLiver abscess6
8 (M/76)Total hip prosthesis+ (TP)S, C (Streptococcus bovis)Infected total hip prosthesis3
9 (M/42)Calcaneus+ (TP)C (streptococci, S. epidermidis)Osteomyelitis of calcaneus4
10 (F/64)Calcaneus+ (TP)S, H (chronic osteomyelitis)Osteomyelitis of calcaneus4
11 (M/53)Ankle+ (TP)SOsteomyelitis of ankle4
12 (M/63)Total hip prosthesis− (TN)R, FUSpinal stenosis, no infection5
13 (F/76)Total hip prosthesis+ (TP)SInfected total hip prosthesis4
14 (M/76)Elbow prosthesis+ (TP)SInfected elbow prosthesis4
15 (M/63)Knee prosthesis− (TN)R, FUAseptic loosening8
16 (F/67)Knee− (TN)R, FUOsteoarthritis9
17 (F/72)Knee prosthesis±* (FN)S, CInfected knee prosthesis9
18 (F/65)Knee prosthesis− (TN)R, FUArthrofibrosis4
19 (M/44)Knee− (TN)S, C, FUOsteoarthritis6
20 (F/58)Total hip prosthesis− (TN)S, C, FUAseptic loosening5
  • * ± = results were considered equivocal; slightly increased uptake of 99mTc-IL-8 was seen at medial side of tibia.

  • TP = true-positive; C = culturing; TN = false-negative; R = radiology; FU = clinical follow-up of at least 3 mo without antibiotic treatment; S = surgery; H = histology; FN = false-negative.