Patient (sex/age [y]) | Suspected focus | 99mTc-IL-8 scintigraphy results | Verification | Final diagnosis | Follow-up (mo) |
---|---|---|---|---|---|
1 (F/53) | Pelvic abscess with fistula | + (TP) | C (Pseudomonas aeruginosa) | Pelvic abscess with fistula | 3 |
2 (M/61) | Caval filter | − (TN) | R, FU | Caval filter not infected | 18 |
3 (M/76) | Knee prosthesis | + (TP) | S, H (chronic inflammation and osteomyelitis | Infected knee prosthesis | 12 |
4 (M/66) | Vertebral osteomyelitis | − (FN) | S, C (Escherichia coli) | Vertebral osteomyelitis | 3 |
5 (M/31) | Humerus | + (TP) | C (Staphylococcus epidermidis) | Osteomyelitis of shoulder | 11 |
6 (M/74) | Ankle | − (TN) | H (leukocytoclastic vasculitis), FU | Vasculitis, no infection | 6 |
7 (M/21) | Liver | + (TP) | C (Staphylococcus aureus), S | Liver abscess | 6 |
8 (M/76) | Total hip prosthesis | + (TP) | S, C (Streptococcus bovis) | Infected total hip prosthesis | 3 |
9 (M/42) | Calcaneus | + (TP) | C (streptococci, S. epidermidis) | Osteomyelitis of calcaneus | 4 |
10 (F/64) | Calcaneus | + (TP) | S, H (chronic osteomyelitis) | Osteomyelitis of calcaneus | 4 |
11 (M/53) | Ankle | + (TP) | S | Osteomyelitis of ankle | 4 |
12 (M/63) | Total hip prosthesis | − (TN) | R, FU | Spinal stenosis, no infection | 5 |
13 (F/76) | Total hip prosthesis | + (TP) | S | Infected total hip prosthesis | 4 |
14 (M/76) | Elbow prosthesis | + (TP) | S | Infected elbow prosthesis | 4 |
15 (M/63) | Knee prosthesis | − (TN) | R, FU | Aseptic loosening | 8 |
16 (F/67) | Knee | − (TN) | R, FU | Osteoarthritis | 9 |
17 (F/72) | Knee prosthesis | ±* (FN) | S, C | Infected knee prosthesis | 9 |
18 (F/65) | Knee prosthesis | − (TN) | R, FU | Arthrofibrosis | 4 |
19 (M/44) | Knee | − (TN) | S, C, FU | Osteoarthritis | 6 |
20 (F/58) | Total hip prosthesis | − (TN) | S, C, FU | Aseptic loosening | 5 |
↵* ± = results were considered equivocal; slightly increased uptake of 99mTc-IL-8 was seen at medial side of tibia.
TP = true-positive; C = culturing; TN = false-negative; R = radiology; FU = clinical follow-up of at least 3 mo without antibiotic treatment; S = surgery; H = histology; FN = false-negative.