TABLE 3

Tissue-to-Plasma Input Radioactivity Ratio

Tissue typeFastingHyperinsulinemiaP
Liver52.6 ± 21.9138.8 ± 21.80.03
Visceral fat12.8 ± 3.486.2 ± 29.80.06
Subcutaneous fat8.5 ± 3.329.8 ± 8.70.05
Pancreas13.1 ± 3.771.9 ± 22.70.04
Intestine22.9 ± 4.767.6 ± 17.90.05
Skeletal muscle7.3 ± 1.226.4 ± 8.40.06
Heart93.9 ± 41.6236.2 ± 59.40.12
Cerebellum15.8 ± 3.547.5 ± 26.80.28
Cortex13.4 ± 3.930.9 ± 7.10.07
Corpus callosum21.2 ± 5.533.7 ± 8.80.27
  • Input is represented by intact 18F-FTHA radioactivity levels in arterial plasma in all organs, with exception of liver, in which combined contribution of portal venous and arterial input concentrations was used.