Analysis of CT and PET for Detecting Primary Tumors and Neck Disease in Patients with Salivary Gland Cancers
| Factor on which analysis was based | Imaging modality | No. of findings that were: | % (95% Confidence interval) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TP | FP | FN | TN | Sensitivity | Specificity | Accuracy | PPV | NPV | |||||||||
| Primary tumors (n = 34) | CT | 27 | 7 | 79.4 | |||||||||||||
| 18F-FDG PET | 31 | 3 | 91.2 | ||||||||||||||
| Patients with positive findings in neck (n = 28)* | CT | 12 | 3 | 3 | 10 | 80.0 (51–95) | 76.9 (46–94) | 78.6 (48–95) | 80.0 (51–95) | 76.9 (46–94) | |||||||
| 18F-FDG PET | 14 | 2 | 1 | 11 | 93.3 (68–99) | 84.6 (54–98) | 89.3 (61–98) | 87.5 (63–98) | 91.7 (61–99) | ||||||||
| Cervical levels with metastases (n = 117)* | CT | 23 | 6 | 18 | 70 | 56.1 (39–71) | 92.1 (83–97) | 79.5 (69–87) | 79.3 (62–92) | 79.5 (69–87) | |||||||
| 18F-FDG PET/CT | 33 | 8 | 8 | 68 | 80.5 (65–91) | 89.5 (80–95) | 86.3 (62–94) | 80.5 (65–91) | 89.5 (80–95) | ||||||||
↵* Analyzed only in 28 patients who underwent dissection of total 117 cervical levels; data for 6 patients who did not have neck dissection were excluded.
TP = true-positive; FP = false-positive; FN = false-negative; TN = true-negative; PPV = positive predictive value; NPV = negative predictive value.