lCMRglc Determined by Autoradiography*
| lCMRglc (mean ± SD μmol/g/min) in: | ||||
|---|---|---|---|---|
| Studies with paired animals receiving: | All studies, with animals receiving: | |||
| Structure | 14C-DG (n = 3) | 14C-FDG (n = 3) | 14C-DG (n = 8) | 14C-FDG (n = 6) |
| Cerebellar cortex | 0.55 ± 0.07 | 0.85 ± 0.08 | 0.59 ± 0.07 | 0.89 ± 0.07 |
| Cerebellar white matter | 0.32 ± 0.03 | 0.68 ± 0.05 | 0.39 ± 0.07 | 0.68 ± 0.04 |
| Inferior colliculus | 1.16 ± 0.13 | 1.74 ± 0.24 | 1.24 ± 0.16 | 1.74 ± 0.18 |
| Superior colliculus | 0.80 ± 0.04 | 1.13 ± 0.13 | 0.86 ± 0.11 | 1.24 ± 0.17 |
| Visual cortex | 0.95 ± 0.06 | 1.41 ± 0.20 | 1.00 ± 0.11 | 1.51 ± 0.17 |
| Superior olive | 1.04 ± 0.18 | 1.53 ± 0.24 | 1.15 ± 0.17 | 1.64 ± 0.21 |
| Lateral lemniscus | 0.93 ± 0.08 | 1.33 ± 0.27 | 1.07 ± 0.14 | 1.45 ± 0.24 |
| Auditory cortex | 1.12 ± 0.07 | 1.58 ± 0.29 | 1.16 ± 0.09 | 1.71 ± 0.24 |
| Medial geniculate body | 1.00 ± 0.06 | 1.51 ± 0.33 | 1.07 ± 0.09 | 1.58 ± 0.26 |
| Lateral geniculate body | 0.83 ± 0.014 | 1.19 ± 0.24 | 0.86 ± 0.11 | 1.25 ± 0.17 |
| Internal capsule | 0.34 ± 0.04 | 0.59 ± 0.04 | 0.39 ± 0.06 | 0.63 ± 0.05 |
| Caudate putamen | 1.02 ± 0.10 | 1.38 ± 0.26 | 1.00 ± 0.13 | 1.46 ± 0.21 |
| Lumped constant for FDG | 0.71 ± 0.12 | 0.68 ± 0.03 | ||
↵* Rate constants for white matter were used to compute lCMRglc of cerebellar white matter and internal capsule; for all other structures, rate constants for gray matter were used. Lumped constants for FDG of 0.71 ± 0.12 and 0.68 ± 0.03, obtained in paired and unpaired animals, were not statistically significantly different.