TABLE 2

PCa-to-Tissue Accumulation Ratios of Anti-18F-FACBC and 18F-FDG in DPCI Rats (n = 3)

Anti-18F-FACBC18F-FDG
Tissue*15 min60 min15 min60 min
Urinary bladder0.78 ± 0.590.54 ± 0.120.02 ± 0.010.02 ± 0.01
Blood3.30 ± 0.563.71 ± 0.781.33 ± 0.104.73 ± 0.34
Muscle5.14 ± 0.993.25 ± 0.395.13 ± 0.567.18 ± 3.91
Bone2.49 ± 0.492.80 ± 0.761.95 ± 0.411.87 ± 0.62
Lymph node3.32 ± 1.394.13 ± 0.831.34 ± 0.301.56 ± 0.51
Lung1.69 ± 0.161.93 ± 0.281.36 ± 0.201.69 ± 0.53
Liver0.83 ± 0.261.01 ± 0.161.35 ± 0.124.98 ± 1.15
Brain8.56 ± 0.394.16 ± 0.830.59 ± 0.190.47 ± 0.15
  • * All ratios were calculated from values of %ID/g, except for ratio of PCa to urinary bladder.

  • Ratios were calculated from values of %ID/cm3.

  • P < 0.05, anti-18F-FACBC vs. 18F-FDG at 15 and 60 min after injection.

  • Data are presented as mean ± SD.