TABLE 1

Bayesian Constraints for 4K Model

Parameter^*	Units	Mean^†	SD^†
A₁	PET units^‡	11.8 × 10⁻²	9.14 × 10⁻²
A₂	PET units^‡	9.27 × 10⁻³	4.46 × 10⁻³
A₃	PET units^‡	2.07 × 10⁻³	1.31 × 10⁻³
λ₁	min⁻¹	9.21 × 10⁰	4.99 × 10⁰
λ₂	min⁻¹	1.78 × 10⁻¹	0.76 × 10⁻¹
λ₃	min⁻¹	1.54 × 10⁻²	0.53 × 10⁻²
λ₄	min⁻¹	41.0 × 10⁰	0.65 × 10⁰
k_Q,liver	mL min⁻¹	4.75 × 10⁻¹	0.24 × 10⁻¹
V_T,liver	mL	8.85 × 10⁻¹	0.52 × 10⁻¹
V_E,liver	mL	3.45 × 10⁻¹	0.45 × 10⁻¹
k_P,liver	mL min⁻¹	4.05 × 10⁻³	2.54 × 10⁻³
R_liver	Dimensionless	4.74 × 10⁰	1.13 × 10⁰
k_Q,muscle	mL min⁻¹	1.32 × 10⁻¹	0.54 × 10⁻¹
V_T,muscle	mL	4.89 × 10⁰	0.12 × 10⁰
V_E,muscle	mL	3.37 × 10⁻¹	0.32 × 10⁻¹
k_P,muscle	mL min⁻¹	5.16 × 10⁻²	3.24 × 10⁻²
R_muscle	Dimensionless	51.8 × 10⁰	53.6 × 10⁰

↵* , , , k₄=k_P·(R·V_E)⁻¹.
↵† Population mean and SD of parameters calculated by fitting model to all available data (15,16,18,24) from studies m10861, m11043, m11122, m17156, m17464, and m17709.
↵‡ 1 PET unit ≈ 534 MBq·mL⁻¹.