TABLE 5

Supplemental Data: Matrix of Combinations of Pre-PET and Post-PET Management Plans and Their Classification

	Pre-PET plan
Post-PET plan	Watch	More imaging	Tissue biopsy	Curative surgery	Palliative surgery	Curative chemotherapy	Palliative chemotherapy	Curative radiation	Palliative radiation	Supportive care
Watch	No change	Minor	Minor	Major	Major	Major	Major	Major	Major	Minor
More imaging	Minor	No change	Minor	Major	Major	Major	Major	Major	Major	Minor
Tissue biopsy	Minor	Minor	No change	Major	Major	Major	Major	Major	Major	Minor
Curative surgery	Major	Major	Major	No change	Minor	Major mode	Major mode	Major mode	Major mode	Major
Palliative surgery	Major	Major	Major	Minor	No change	Major mode	Major mode	Major mode	Major mode	Major
Curative chemotherapy	Major	Major	Major	Major mode	Major mode	No change	Minor	Major mode	Major mode	Major
Palliative chemotherapy	Major	Major	Major	Major mode	Major mode	Minor	No change	Major mode	Major mode	Major
Curative radiation	Major	Major	Major	Major mode	Major mode	Major mode	Major mode	No change	Minor	Major
Palliative radiation	Major	Major	Major	Major mode	Major mode	Major mode	Major mode	Minor	No change	Major
Supportive care	Minor	Minor	Minor	Major	Major	Major	Major	Major	Major	No change

Minor = trivial change scored; Major = substantial increase or decrease in intensity of care between management plans; Major mode = substantial change in type of therapy even if treatment goal is unchanged.
2-category scoring: No change and Major (collapsing no change and Minor as well Major and Major mode); 3-category scoring: No change, Minor, and Major (collapsing Major and Major mode); 4-category scoring: No change, Minor, Major, and Major mode.