Tissue-to-Muscle Ratios Measured by Different Methods
| Tissue-to-muscle ratio (SD) (n = 3) for: | |||||
|---|---|---|---|---|---|
| Method | Kidneys | U87MG tumor | Bone | Spleen | Liver |
| In vivo PET | 1.9 (0.6) | 4.1 (1.1) | 14.4 (0.5) | 33.9 (10.5) | 100.7 (22.1) |
| In vivo PET (DOTA–QD) | 1.3 (0.1) | 1.0 (0.0) | 11.7 (7.2) | 28.2 (3.1) | 82.6 (2.7) |
| Ex vivo PET | 3.1 | 5.2 | 10.0 | 33.7 | 200.0 |
| NIRF imaging | 0.8 | 2.0 | 40.5 | 47.6 | 106.8 |
| Homogenate fluorescence | 0.6 (0.0) | 2.2 (0.0) | 8.6 (0.1) | 44.2 (1.2) | 76.1 (2.8) |
All data are for mice injected with 64Cu-labeled DOTA–QD–RGD unless stated otherwise.