TABLE 2

Radiation Dose Estimates for [18F]SPA-RQ in Standard Reference Man

Thin-sliceBisected2D planar
Target organμGy/MBqμGy/MBqRatio to thin-sliceμGy/MBqRatio to thin-slice
Lungs81.881.20.9980.10.98
ULI wall78.267.60.8658.20.74
Small intestine69.560.20.87520.75
Urinary bladder wall56.857.41.0158.41.03
Kidneys56.468.31.21921.63
Thyroid31.341.71.3361.61.97
Liver30.227.60.9130.41.01
LLI wall28.925.70.8922.60.78
Red marrow28.115.80.5614.80.53
Osteogenic cells18.212.60.69120.66
Testes17.430.51.7645.22.6
Ovaries16.915.70.9313.40.79
Brain15.816.51.0416.81.06
Gallbladder wall15.715.20.9715.20.97
Heart wall15.519.71.2835.92.32
Uterus15.314.80.9713.80.9
Adrenals12.312.31.0013.11.06
Pancreas10.911.31.0411.81.08
Total body10.410.30.9910.30.99
Stomach wall9.29.71.059.61.05
Spleen8.59.41.19.91.16
Thymus7.58.21.18.61.15
Muscle6.87.31.077.21.05
Breasts6.36.81.096.91.11
Skin4.14.61.144.61.12
μSv/MBqμSv/MBqRatio to thin-sliceμSv/MBqRatio to thin-slice
ED equivalent37.637.30.9940.61.08
ED29.529.30.9932.31.10
  • A 2.4-h urine voiding interval was assumed for all 3 methods.