TABLE 1

Percent Change in HED Uptake After Pharmacologic Treatment in Tissues Exhibiting NET-Specific Retention

Treatment and doseLeft ventricleBrown adiposeLungPancreas
Desipramine (n = 7), 10 mg/kg 30 min earlier−89−71−60−50
Nisoxetine (n = 6), 10 mg/kg 30 min earlier−85−57−53−49
Metaraminol (n = 6), 1.3 mg/kg intravenous coinjection−88−63−58−54
  • Percent change = ([%ID/g treated] − [%ID/g control])/(%ID/g control) × 100%.

  • Values presented represent significant deviation (P < 0.05) in %ID/g treated as compared with untreated controls.