Progression-Free Survival Estimates for Predefined Metabolic Response Categories
| Median and 1-, 2-, and 3-y progression-free survival rates (PFS) for EORTC metabolic response categories | |||||
|---|---|---|---|---|---|
| Median PFS (mo) | 1-y PFS (%) | 2-y PFS (%) | 3-y PFS (%) | P value | |
| CR/PR: ΔMRGlu < −25% | 8 | 33 | 19 | 9 | 0.007 |
| SD: ΔMRGlu −25% to +25% | 3 | 9 | 0 | 0 | |
| PD: ΔMRGlu > +25% | 1 | 0 | 0 | 0 | |
| CR/PR: ΔSUV < −25% | 11 | 39 | 26 | 16 | 0.0003 |
| SD: ΔSUV −25% to +25% | 3 | 13 | 6 | 0 | |
| PD: ΔSUV > +25% | 0 | 0 | 0 | 0 | |
| Median and 1-, 2-, and 3-y progression-free survival rates (PFS) for metabolic response categories applying cutoff levels that are used for clinical response with conventional methods (size measurement) according to RECIST | |||||
| Median PFS (mo) | 1-y PFS (%) | 2-y PFS (%) | 3-y PFS (%) | P value | |
| CR/PR: ΔMRGlu < −30% | 10 | 36 | 21 | 10 | 0.006 |
| SD: ΔMRGlu −30% to +20% | 3 | 9 | 0 | 0 | |
| PD: ΔMRGlu > +20% | 1 | 0 | 0 | 0 | |
| CR/PR: ΔSUV < −30% | 11 | 42 | 28 | 17 | 0.0003 |
| SD: ΔSUV −30% to +20% | 3 | 11 | 0 | 0 | |
| PD: ΔSUV > +20% | 0 | 0 | 0 | 0 | |