TABLE 2

Risk Factors for Early (n = 176) and Late (n = 121) Endpoints

Endpoint	Risk factor^*	Odds ratio unadjusted	P value	Odds ratio adjusted^†	P value
Sialadenitis^‡	Age	0.997 (0.98–1.02)	0.79	0.99 (0.97–1.02)	0.59
	Male	0.67 (0.32–1.39)	0.28	0.59 (0.26–1.37)	0.22
	Iodine activity	1.03 (0.96–1.10)	0.40	1.03 (0.94–1.13)	0.53
	Iodine score	1.28 (1.04–1.58)	0.020	1.31 (1.05–1.63)	0.015
Xerostomia^‡	Age	0.99 (0.97–1.02)	0.55	1.00 (0.98–1.03)	0.76
	Male	1.66 (0.74–3.75)	0.22	1.79 (0.92–3.48)	0.09
	Iodine activity	1.11 (0.98–1.25)	0.088	1.15 (1.04–1.29)	0.010
	Iodine score	1.52 (1.09–2.11)	0.014	1.58 (1.16–2.16)	0.004
	Sialadenitis	2.37 (1.28–4.41)	0.006	2.88 (1.64–5.07)	0.001
		% increase unadjusted		% increase adjusted^†
Caries^§	Age	1.5 (−0.1 to 3.2)	0.07	1.4 (−0.3 to 3.2)	0.12
	Male	−13.1 (−51.2 to 54.8)	0.63	−11.0 (−32.7 to 82.8)	0.68
	Iodine activity	−2.0 (−9.6 to 6.3)	0.63	−3.2 (−9.5 to 3.4)	0.33
	Iodine score	−3.1 (−27.5 to 29.7)	0.83	−14.7 (−33.9 to 10.1)	0.22
	Sialadenitis	35.9 (−7.5 to 99.9)	0.12	−15.6 (−41.9 to 22.5)	0.37
	Xerostomia	82.0 (10.9 to 199)	0.018	98.8 (26.5 to 212)	0.003
	Prior caries	39.3 (18.6 to 63.7)	0.001	32.2 (12.0 to 56.1)	0.001
	Tooth brushing	10.6 (−18.3 to 49.7)	0.52	−10.4 (−37.5 to 28.5)	0.55
Tooth extraction^§^‖	Age	−1.32 (−4.40,1.85)	0.41	−0.72 (−4.27, 2.97)	0.70
	Male	−26.4 (−75.0–116.5)	0.58	−45.1 (−85.4,106)	0.37
	Iodine activity	6.91 (0.74–13.5)	0.03	8.14 (1.07, 15.7)	0.02
	Iodine score	−7.5 (−43.8–52.4)	0.76	−1.19 (−41.6, 67.2)	0.96
	Sialadenitis	16.3 (−33.9, 105)	0.60	−10.6 (−56.2, 82.3)	0.76
	Xerostomia	2.24 (−58.9, 154)	0.96	−25.7 (−73.1, 105)	0.57
	Prior caries	1.14 (−30.6, 47.3)	0.95	7.50 (−29.6, 64.1)	0.74
	Date of radioiodine therapy	−5.46 (10.3,-0.42)	0.03	−5.11 (−10.9, 1.02)	0.10
	Tooth brushing	−28.7 (−64.0, 41.3)	0.33	−39.6 (−72.1, 30.7)	0.20

↵* The respective units are as follows: age, per year; male, vs. female; iodine activity, per GBq; iodine score, per gland; sialadenitis, per gland affected; prior caries, per site; tooth brushing, times per day.
↵† Adjusted for all other covariates in the list.
↵‡ Estimates were obtained from binomial regression models and refer to individual sites.
↵§ Estimates were obtained from Poisson regression models and refer to individual sites.
↵‖ Number of tooth extractions after radioiodine therapy in patients without prior extractions.
Corresponding 95% confidence intervals are in parentheses. Boldface type indicates statistical significance of the respective covariate.