TABLE 3

Characteristics of Benign Lesions

Visual uptake grading
Patient no.DiagnosisUS*XMMSMM
10Fibrocystic changes, other (fat)No lesionNo lesion2
13Fibrocystic changes221
174 Fibrocystic changes222 (FNAC)§, 3 others
18Fibroadenoma221
19Infectious cyst223
20Fibroadenoma321
  • * US: 5-scale grading, where grade 2 = benign finding and grade 3 = indeterminate.

  • XMM: findings are graded according to BIRADS, where grade 1 = negative, grade 2 = benign finding, grade 3 = probably benign finding, grade 4 = suspicious abnormality (biopsy should be considered), and grade 5 = highly suggestive of malignancy.

  • SMM with NC100692 administration (study drug): 3-grade scale, where grade 1 = no obvious uptake, grade 2 = uncertain/heterogeneous uptake, and grade 3 = focal lesion uptake.

  • § FNAC = lesion had fine-needle aspiration cytology before scintigraphy.

  • BIRADS = Breast Imaging Reporting and Data System.