Tumor | 64Cu uptake area fraction* | EF5 staining area fraction | Spatial correlation* |
---|---|---|---|
R3230Ac (n = 8) | 0.239 ± 0.036 | 0.207 ± 0.025 | 0.74 ± 0.02, P < 0.001 |
9L (n = 7) | 0.166 ± 0.067 | 0.208 ± 0.051 | 0.61 ± 0.04, P < 0.001 |
FSA (n = 7) | 0.442 ± 0.094 | 0.165 ± 0.041† | 0.11 ± 0.03, P = 0.2 |
↵* 64Cu-ATSM autoradiography images were used for area fraction and spatial correlation analysis. Area fraction is defined as ratio of positive staining or uptake region to overall viable tissue.
↵† P < 0.05, significant difference between 64Cu-ATSM uptake and EF5 staining area fractions for FSA.
Data are presented as mean ± SEM.