TABLE 1

Animal Parameters, Radioactivity Dosage, and 64Cu-ATSM Uptake in 3 Tumor Lines

TumorAnimal weight (g)Tumor volume (cm3)Dose (MBq)SUV*T/M ratio†
R3230Ac (n = 8)179.00 ± 6.865.59 ± 1.7426.5 ± 2.71.31 ± 0.112.29 ± 0.22
9L (n = 7)225.86 ± 7.467.17 ± 2.1325.0 ± 2.11.64 ± 0.11‡3.43 ± 0.22‡
FSA (n = 7)154.14 ± 8.874.81 ± 1.2026.1 ± 2.52.04 ± 0.105.33 ± 0.25

  • ↵* SUV is value at 1 h after injection of 64Cu-ATSM.

  • ↵† T/M ratio is taken at 1 h after injection of 64Cu-ATSM.

  • ↵‡ P < 0.05 (9L vs. R3230Ac).

  • ↵ P < 0.001 (FSA vs. R3230Ac/9L).

  • Data are presented as mean ± SEM.