TABLE 1

BP Values Calculated from SRTM, and SUR Calculated from TR, with Corresponding Percentages of 123I-R91150 Displacement for Each Region in Each Subject at the 3 Ketanserin Doses

ROISubjectBPpreBPpostSUR180SUR400%DisplSRTM%DisplTR
0.1 mg/kg
 Orbitofrontal10.440.190.550.1457.174.8
20.810.291.000.2664.674.1
 Prefrontal10.410.040.490.0289.995.1
20.680.110.810.1183.387.0
 Superior frontal10.290.010.350.0095.4101.2
20.630.100.720.0984.987.2
 Calcarine occipital10.400.130.480.1368.771.9
20.710.130.780.1382.282.9
 Lateral occipital10.420.080.480.0879.882.9
20.490.070.570.0386.094.0
 Temporal10.440.110.470.0974.681.3
20.760.220.870.2071.577.5
 Parietal10.270.030.280.0289.891.7
20.620.130.670.1479.679.5
0.05 mg/kg
 Orbitofrontal30.370.180.440.1951.756.7
40.560.270.570.2452.058.6
 Prefrontal30.290.050.350.0682.582.6
40.510.200.540.1761.167.8
 Superior frontal30.270.040.330.0284.592.5
40.400.150.390.1263.570.4
 Calcarine occipital30.410.150.460.0963.581.4
40.420.130.420.1369.869.4
 Lateral occipital30.250.100.280.1160.762.5
40.460.040.450.0991.479.6
 Temporal30.320.150.390.1153.270.9
40.460.160.470.1965.859.2
 Parietal30.170.040.21−0.0176.5102.8
40.420.140.400.1265.571.5
0.015 mg/kg
 Orbitofrontal50.350.320.380.337.713.8
60.700.440.650.5136.420.9
 Prefrontal50.270.230.330.2417.027.8
60.480.270.490.3243.635.4
 Superior frontal50.230.170.280.1825.334.8
60.360.210.420.2342.447.0
 Calcarine occipital50.280.200.330.2126.837.6
60.450.280.540.3038.244.0
 Lateral occipital50.180.130.160.1227.622.8
60.370.170.370.1954.548.5
 Temporal50.280.240.310.2514.819.0
60.640.330.600.4148.031.1
 Parietal50.270.200.300.2125.829.6
60.400.200.420.2550.840.5