TABLE 1

Tissue Distribution of 131I-FIAU–Labeled NG4TL4-TK Cells in FVB/N Mice Bearing Lung-Colonizing Metastatic NG4TL4-TK Sarcoma

Tissue distributionnActivity (%ID/g)*
Blood30.036 ± 0.023
Brain30.029 ± 0.018
Thyroid30.685 ± 0.338
Lung387.1 ± 24.9
Heart30.025 ± 0.011
Stomach30.967 ± 0.558
Liver30.536 ± 0.312
Spleen30.069 ± 0.038
Large intestine30.841 ± 0.361
Small intestine34.97 ± 2.11
Kidney30.138 ± 0.023
Bladder30.008 ± 0.003
Muscle30.044 ± 0.011
Bone30.036 ± 0.019
Abdominal fat30.164 ± 0.068
  • * Percentage injected dose per gram of tissue at 4 d after tail vein injection of 1 × 106 NG4TL4-TK cells labeled with 131I-FIAU, corrected for radioactive decay to time of injection.

  • Data are expressed as mean ± SEM.