TABLE 5

Diagnostic Accuracy of ¹⁸F-FDOPA PET at Various Thresholds for Ratios of Tumor Uptake to Normal Tissue Uptake in Group 1 and Group 2 Patients

Threshold for ratio of tumor uptake to normal tissue uptake	Parameter (%)	Group1 patients (n = 30)	Group2 patients (n = 51)	Combining 2 groups (n = 81)
T/S > 0.75	Sensitivity	100	97	98
	Specificity	86	86	86
	Accuracy	97	94	95
	PPV	96	95	95
	NPV	100	92	95
T/S > 1.0	Sensitivity	96	86	92
	Specificity	100	93	95
	Accuracy	97	88	93
	PPV	100	94	98
	NPV	88	75	80
T/N > 1.3	Sensitivity	96	95	95
	Specificity	86	86	86
	Accuracy	93	94	93
	PPV	96	95	95
	NPV	86	92	86
T/W > 1.6	Sensitivity	96	92	93
	Specificity	86	86	86
	Accuracy	93	84	91
	PPV	96	87	95
	NPV	86	75	82