Biodistribution | 1 h | 4 h | 12 h | 24 h | 48 h | 72 h |
---|---|---|---|---|---|---|
Blood | 2.1 ± 0.3 | 0.12 ± 0.03 | 0.07 ± 0.01 | 0.04 ± 0.01 | 0.02 ± 0.01 | 0.010 ± 0.001 |
Heart | 0.9 ± 0.3 | 0.11 ± 0.05 | 0.12 ± 0.09 | 0.06 ± 0.03 | ||
Lung | 2.3 ± 0.4 | 0.6 ± 0.1 | 0.6 ± 0.1 | 0.37 ± 0.02 | ||
Liver | 2.0 ± 0.3 | 1.6 ± 0.3 | 1.5 ± 0.3 | 1.2 ± 0.2 | 0.76 ± 0.04 | 0.8 ± 0.1 |
Spleen | 1.0 ± 0.1 | 0.56 ± 0.08 | 0.6 ± 0.1 | 0.44 ± 0.08 | ||
Pancreas | 0.7 ± 0.1 | 0.25 ± 0.04 | 0.22 ± 0.03 | 0.14 ± 0.03 | ||
Kidney | 264 ± 36 | 324 ± 22 | 306 ± 50 | 248 ± 10 | 147.9 ± 7.07 | 115 ± 12 |
Stomach | 1.2 ± 0.2 | 0.4 ± 0.1 | 0.36 ± 0.08 | 0.20 ± 0.08 | ||
Small intestine | 1.1 ± 0.1 | 0.5 ± 0.2 | 0.39 ± 0.08 | 0.23 ± 0.08 | ||
Large intestine | 1.4 ± 0.6 | 0.7 ± 0.3 | 0.8 ± 0.2 | 0.59 ± 0.03 | ||
Salivary gland | 1.4 ± 0.2 | 0.51 ± 0.03 | 0.4 ± 0.2 | 0.36 ± 0.03 | ||
Tumor | 12 ± 3 | 12 ± 3 | 14 ± 4 | 8.6 ± 0.9 | 7 ± 4 | 5 ± 1 |
Muscle | 0.4 ± 0.1 | 0.07 ± 0.02 | 0.08 ± 0.02 | 0.04 ± 0.03 | ||
Bone | 0.7 ± 0.3 | 0.3 ± 0.2 | 0.3 ± 0.2 | 0.1 ± 0.1 | ||
Brain | 0.04 ± 0.02 | 0.01 | 0.01 |
Each value represents an average from 4 animals ± SD and is expressed as percentage of injected radioactivity per gram organ or tissue.