Recommendations of Workshop Panel
Parameter | Recommendation |
---|---|
Patient preparation | Patients fast overnight for morning scan or 4 h for afternoon scan. Venous serum glucose concentration is measured before injection (<120 mg/dL for nondiabetic patients and 150–200 mg/dL for diabetic patients). |
Diabetic patients are scanned in morning after overnight fast and before first use of medication. | |
Patients are well hydrated and, if possible, drink 500 mL of water after injection and before scanning. For renal/pelvic imaging, furosemide (20–40 mg) may be given 10–15 min after 18F-FDG injection, or urinary catheter may be used. | |
All medications being taken by patients are recorded. | |
Diazepam or other mild sedative may be used at clinician's discretion to decrease uptake in muscle. | |
PET timing | Pretreatment and posttreatment scans are acquired. |
Pretreatment scans are acquired as close to start of therapy as possible (preferably <2 wk). | |
Posttreatment scans are acquired no sooner than 2 wk after end of chemotherapy to avoid transient increases or decreases. Timing is determined by endpoint being assessed. | |
Timing of scans after changes due to radiotherapy needs further investigation. | |
Whole-body imaging begins 60 ± 10 min after injection of 18F-FDG. | |
Attenuation correction | Attenuation correction is used. No standard procedure has yet been recommended. Procedure chosen is documented. |
18F-FDG dose | No standard dose has yet been recommended. Doses of 370–740 MBq (10–20 mCi) are appropriate. Dose injected is documented. |