TABLE 2

Recommendations of Workshop Panel

ParameterRecommendation
Patient preparationPatients fast overnight for morning scan or 4 h for afternoon scan. Venous serum glucose concentration is measured before injection (<120 mg/dL for nondiabetic patients and 150–200 mg/dL for diabetic patients).
Diabetic patients are scanned in morning after overnight fast and before first use of medication.
Patients are well hydrated and, if possible, drink 500 mL of water after injection and before scanning. For renal/pelvic imaging, furosemide (20–40 mg) may be given 10–15 min after 18F-FDG injection, or urinary catheter may be used.
All medications being taken by patients are recorded.
Diazepam or other mild sedative may be used at clinician's discretion to decrease uptake in muscle.
PET timingPretreatment and posttreatment scans are acquired.
Pretreatment scans are acquired as close to start of therapy as possible (preferably <2 wk).
Posttreatment scans are acquired no sooner than 2 wk after end of chemotherapy to avoid transient increases or decreases. Timing is determined by endpoint being assessed.
Timing of scans after changes due to radiotherapy needs further investigation.
Whole-body imaging begins 60 ± 10 min after injection of 18F-FDG.
Attenuation correctionAttenuation correction is used. No standard procedure has yet been recommended. Procedure chosen is documented.
18F-FDG doseNo standard dose has yet been recommended. Doses of 370–740 MBq (10–20 mCi) are appropriate. Dose injected is documented.