TABLE 1

Methods of Assessing ¹⁸F-FDG Uptake (1)

Method	Advantage	Disadvantage	Dependency
Visual	Static/whole-body imaging	Subjectivity	Uptake time
	No need for blood sampling	Chance of threshold variation between readers	Blood glucose concentration
	Short scan times	Low statistics	Partial-volume effects
	± Attenuation correction	Single snapshot of dynamic process
		Dependency on background activity
SUV	Static/whole-body imaging	Numerous methods of calculation	Uptake time
	Semiquantitative analysis	Low statistics	Blood glucose concentration
	No need for blood sampling	Single snapshot of dynamic process	Body weight
	Ease of computation	Need for attenuation correction	Partial-volume effects
		Inaccuracy in detecting small changes
Kinetic	Dynamic data acquisition	Need for input function (arterial preferred)	Partial-volume effects
	Quantitative analysis	Complexity of computation	Quality of input function
	Low dependency on imaging time