TABLE 2

Body Weights of BALB/c Mice Intravenously Administered PBS (pH 7.4), HuM195, 111In-HuM195, NLS-HuM195, or 111In-NLS-HuM195

Body weight (g)
DayPBSHuM195111In-HuM195NLS-HuM195111In-NLS-HuM195
014.58 ± 0.5415.67 ± 0.3915.20 ± 0.4715.52 ± 0.3014.90 ± 0.43
815.45 ± 0.5216.70 ± 0.2416.01 ± 0.3815.97 ± 0.4315.45 ± 0.50
1516.36 ± 0.7017.46 ± 0.0916.70 ± 0.4216.87 ± 0.4516.32 ± 0.39
  • Groups of 4 BALB/c mice were administered 3.7 MBq (22 μg) of 111In-HuM195 or 111In-NLS-HuM195, 22 μg of their corresponding nonradiolabeled forms, or PBS by intravenous injection (tail vein).