TABLE 1

Clinical Biochemistry and Hematology Parameters in BALB/c Mice Intravenously Administered PBS (pH 7.4), 111In-HuM195, or 111In-NLS-HuM195

ParameterPBS111In-HuM195111In-NLS-HuM195Normal range*
WBC (× 109/L)5.44.74.05.0–13.7
RBC (× 1012/L)6.3ND8.77.9–10.1
Hb (g/L)141143146110–145
Hct0.4160.4160.4280.400
Platelets (× 109/L)764600558600–1,200
ALT (units/L)89394228–184
Cr (μmol/L)181626NA
  • * Normal range values from (20).

  • WBC = white blood cells; RBC = red blood cells; ND = not determined; NA = not available.