TABLE 3

Renogram Parameters for Whole-Kidney Regions of Interest with 99mTc(CO)3(meso-LAN) and 99mTc(CO)3(dd,ll-LAN) Compared with 131I-OIH in Humans (n = 3)

Left kidneyRight kidneyLeft kidneyRight kidney
Isomer% 99mTc% 131I-OIHTTP (min) for 99mTcTTP (min) for 131I-OIHTTP (min) for 99mTcTTP (min) for 131I-OIH20 min/max for 99mTc20 min/max for 131I-OIH20 min/max for 99mTc20 min/max for 131I-OIH
meso-LAN47 ± 8.146 ± 7.04.66 ± 2.492.65 ± 0.533.58 ± 0.323.08 ± 0.590.35 ± 0.100.12 ± 0.090.29 ± 0.030.07 ± 0.02
dd,ll-LAN60 ± 2.162 ± 4.23.17 ± 0.623.15 ± 0.753.01 ± 0.573.55 ± 0.190.39 ± 0.070.12 ± 0.060.33 ± 0.080.08 ± 0.04
  • TTP = time to peak height of renogram curve; 20 min/max = ratio of counts in kidney at 20 min after injection to maximum counts.

  • Data are mean ± SD.