TABLE 3

Uptake of l- and d-¹⁸F-FMT in Tumor-Bearing Mice

Organ	Isomer	5 min	15 min	30 min	60 min
Blood	l	1.175 ± 0.024	1.010 ± 0.030	0.852 ± 0.024	0.747 ± 0.029
	d	1.492 ± 0.045	0.699 ± 0.055	0.474 ± 0.018	0.391 ± 0.045
Heart	l	1.180 ± 0.079	1.012 ± 0.025	0.925 ± 0.031	0.838 ± 0.030
	d	1.034 ± 0.024	0.805 ± 0.055	0.608 ± 0.041	0.368 ± 0.014
Lung	l	1.117 ± 0.045	0.923 ± 0.019	0.864 ± 0.007	0.787 ± 0.031
	d	1.332 ± 0.035	0.832 ± 0.038	0.528 ± 0.028	0.325 ± 0.018
Liver	l	1.047 ± 0.014	0.846 ± 0.016	0.815 ± 0.032	0.675 ± 0.025
	d	1.493 ± 0.046	0.738 ± 0.044	0.468 ± 0.013	0.325 ± 0.031
Kidney	l	1.323 ± 0.032	1.177 ± 0.027	1.034 ± 0.052	0.858 ± 0.055
	d	4.550 ± 0.879	1.448 ± 0.083	0.958 ± 0.076	0.610 ± 0.081
Spleen	l	1.533 ± 0.080	1.451 ± 0.088	1.418 ± 0.145	1.070 ± 0.013
	d	1.370 ± 0.046	1.037 ± 0.094	0.805 ± 0.029	0.616 ± 0.259
Muscle	l	1.066 ± 0.069	1.007 ± 0.046	0.842 ± 0.038	0.716 ± 0.015
	d	0.481 ± 0.015	0.575 ± 0.038	0.538 ± 0.014	0.482 ± 0.040
Bone	l	0.929 ± 0.033	0.888 ± 0.026	0.965 ± 0.007	1.143 ± 0.031
	d	0.772 ± 0.016	0.701 ± 0.049	0.713 ± 0.009	0.686 ± 0.042
Intestine	l	1.120 ± 0.033	1.002 ± 0.084	0.837 ± 0.058	0.805 ± 0.074
	d	1.041 ± 0.048	0.718 ± 0.076	0.475 ± 0.062	0.306 ± 0.015
Gut	l	0.898 ± 0.041	1.161 ± 0.666	0.703 ± 0.034	0.609 ± 0.032
	d	0.532 ± 0.040	0.514 ± 0.027	0.353 ± 0.026	0.217 ± 0.020
Pancreas	l	6.601 ± 0.257	7.873 ± 1.088	9.199 ± 0.530	6.243 ± 0.715
	d	7.658 ± 1.621	5.187 ± 1.815	3.853 ± 0.655	2.385 ± 0.264
Brain	l	ND	ND	ND	0.725 ± 0.233
	d	ND	ND	ND	0.382 ± 0.071
Tumor	l	1.478 ± 0.119	2.271 ± 0.457	2.801 ± 0.164	2.700 ± 0.329
	d	1.315 ± 0.248	2.129 ± 0.311	2.489 ± 0.188	2.570 ± 0.547

ND = not determined.
Mice (n = 5 at each time point) were injected intravenously with 5 MBq of l- or d-¹⁸F-FMT via tail vein and killed at 5, 15, 30, and 60 min after injection; tissue samples were rapidly removed, and weight and radioactivity were measured. Data are expressed as SUV.