TABLE 7

Model Results for Various 131I-MIBG Marrow Doses per Megabecquerel

mMIBG (mGy/MBq)
Parameter0.0240.0480.0720.0960.12
αopt0.810.770.760.760.75
βopt0.740.880.920.940.95
tDOTA/tMIBG maximum7.913.922.611.961.57
Maximum fractional increase0.550.650.680.700.71
tDOTA/tMIBG*2.051.010.680.510.41
tDOTA/tMIBG†24.2424.2424.2424.2424.24
tDOTA/tMIBG 0.25*4.732.131.391.030.82
tDOTA/tMIBG 0.25†12.458.085.994.773.95

  • ↵* Lower level for tumor-dose ratio.

  • ↵† Upper level for tumor-dose ratio.