TABLE 1

Individual Patient Data and Time Span Between Initial Diagnosis and Suspected Recurrence

Patient no.Original diagnosisProof of diagnosisTreatment during course of diseaseMRI contrast enhancement at biopsyBiopsy resultTime since diagnosis (mo)
1AIIBiopsySeedsPositiveAII81
2AIIBiopsySeedsPositiveAII30
3AIIBiopsySeedsPositiveAII20
4AIIBiopsySeedsPositiveAII54
5AIIBiopsySeedsPositiveAII13
6AIIBiopsySeedsPositiveGBM41
7AIIBiopsyRadPositiveAII14
8AIIBiopsyRad, ChPositiveAII48
9AIISurgery2x SurgeryPositiveNo TU61
10AIISurgerySurgeryPositiveAIII7
11AIISurgery4x Surgery, RadPositiveGBM251
12AIISurgerySurgery, RadPositiveAII67
13AIISurgery2x Surgery, RadPositiveAII79
14AIISurgerySurgery, RadPositiveAIII155
15AIISurgerySurgery, RadPositiveAIII43
16AIISurgery2x Surgery, Rad, ChPositiveAIII107
17AIISurgerySurgery, Rad, ChPositiveAIII41
18AIISurgery3x Surgery, Rad, ChPositiveAIII152
19AIISurgerySurgery, Rad, ChPositiveAII47
20AIISurgerySurgery, SeedsPositiveAII10
21AIISurgerySurgery, SeedsPositiveAII35
22AIISurgerySurgery, SeedsPositiveAII28
23OAIIBiopsySeedsPositiveOAII31
24OAIISurgerySurgery, RadPositiveOAII102
25OAIISurgerySurgery, Rad, SeedsPositiveOAII161
26OAIISurgerySurgeryPositiveOAIII41
27AIIIBiopsyRad, RITPositiveGBM74
28AIIISurgerySurgery, RadPositiveAIII21
29AIIISurgerySurgery, RadPositiveGBM11
30AIIISurgerySurgery, RadPositiveNo TU10
31AIIISurgerySurgery, Rad, ChPositiveAIII7
32AIIISurgerySurgery, Rad, Ch, SeedsPositiveAIII55
33AIIISurgerySurgery, Rad, RITPositiveNo TU70
34GBMSurgerySurgery, RadPositiveGBM10
35GBMSurgerySurgery, RadPositiveGBM4
36GBMSurgerySurgery, RadPositiveGBM4
37GBMSurgerySurgery, RadPositiveGBM8
38GBMSurgerySurgery, RadPositiveGBM4
39GBMSurgerySurgery, RadPositiveNo TU12
40GBMSurgerySurgery, Rad, ChPositiveGBM9
41GBMSurgerySurgery, Rad, ChPositiveGBM6
42GBMSurgery2x Surgery, Rad, ChPositiveGBM22
43GBMSurgerySurgery, Rad, RITPositiveGBM10
44GBMSurgerySurgery, Rad, RITPositiveGBM12
45GBMSurgerySurgery, Rad, SeedsPositiveGBM14
  • AII = astrocytoma, WHO II; Seeds = temporary implantation of 125I-seeds; GBM = glioblastoma, WHO IV; Rad = external radiation therapy; Ch = systemic chemotherapy; no TU = no evidence of vital tumor; AIII = anaplastic astrocytoma, WHO III; OAII = oligoastrocytoma, WHO II; OAIII = anaplastic oligoastrocytoma, WHO III; RIT = intracavitary radioimmunotherapy with 131I-tenascin antibodies.