TABLE 3

Hemodynamic, MVO₂, and Efficiency Data

	Severe heart failure with LBBB
Parameter	Baseline	4 mo of CRT	13 mo of CRT	Mild heart failure without LBBB
Heart rate (bpm)	74 ± 13	72 ± 11	65 ± 9	69 ± 11
Systolic BP (mm Hg)	105 ± 27^*	113 ± 21	113 ± 23	129 ± 25
Diastolic BP (mm Hg)	68 ± 10^*	68 ± 14^*	64 ± 12^*	81 ± 13
k₂ (min⁻¹)	0.081 ± 0.015^*	0.082 ± 0.016^*	0.086 ± 0.020	0.099 ± 0.023
CV of regional k₂	0.112 ± 0.048^*	0.066 ± 0.038^†	0.069 ± 0.039^†	0.063 ± 0.014
SVI (mL/m²)	38 ± 16^*	50 ± 15^†	57 ± 12^†	55 ± 17
CE (10⁶ × mL/m² × mm Hg)	3.47 ± 1.34^*	4.91 ± 1.35^†	4.85 ± 1.29^†	4.77 ± 0.72

↵* P < 0.05 vs. comparison group with mild heart failure.
↵† P < 0.05 vs. baseline.
BP = blood pressure; k₂ = acetate clearance rate, a measure of MVO₂ rate; CV = coefficient of variation; CE = cardiac efficiency.
Values are mean ± SD.