Hemodynamic and Perfusion Measurements During 15O-Water Studies
| Measurement | Rest (n = 10) | Dobutamine (n = 6) | β-Blocker (n = 2) |
|---|---|---|---|
| HR (BPM) | 266 ± 4 | 350 ± 0* | 236 ± 31 |
| SBP (mm Hg) | 89 ± 15 | 79 ± 18 | 94 ± 19 |
| DBP (mm Hg) | 70 ± 7 | 56 ± 16† | 57 ± 8 |
| RPP (mm Hg·BPM) | 23,637 ± 3,814 | 27,590 ± 6,336 | 22,599 ± 7,445 |
| MBF-M (mL/g/min) | 4.21 ± 1.76 | 3.47 ± 1.81 | 1.37 ± 1.30 |
| MBF-W (mL/g/min) | 4.05 ± 1.44 | 3.74 ± 1.80 | 2.38 ± 1.81 |
↵* P < 0.0001 vs. rest.
↵† P = 0.10 vs. rest.
HR = heart rate; SBP = systolic blood pressure; DBP = diastolic blood pressure; RPP (SBP·HR) = rate·pressure product; MBF-M = MBF measured by microspheres; MBF-W = MBF measured by 15O-water and kinetic modeling.
Nonpaired t test was done to compare rest studies with dobutamine studies only.