Characteristics and Conditioning of Patients Receiving Radioimmunotherapy
| Characteristic | 188Re (n = 93) | 90Y (n = 21) |
|---|---|---|
| Age (y) | ||
| Median | 46 | 49 |
| Range | 17–64 | 18–67 |
| Sex | ||
| Female | 39 | 5 |
| Male | 54 | 16 |
| Diagnosis | ||
| Acute myelogenous leukemia/myelodysplastic syndrome/myeloproliferative syndrome | 57 | 13 |
| Acute lymphoblastic leukemia | 17 | 5 |
| Chronic myelogenous leukemia | 14 | 3 |
| Chronic lymphocytic leukemia/prolymphocytic leukemia | 5 | 0 |
| Stem cell source | ||
| Bone marrow | 9 | 2 |
| Peripheral blood | 84 | 19 |
| Donor | ||
| Matched related | 42 | 8 |
| Matched unrelated | 29 | 9 |
| Mismatched related | 3 | 0 |
| Mismatched unrelated | 7 | 2 |
| Haploidentical | 12 | 2 |
| Conditioning | ||
| TBI, cyclophosphamide | 43 | 3 |
| Busulfan, cyclophosphamide | 26 | 9 |
| TBI, cyclophosphamide, thiotepa | 11 | 1 |
| Fludarabine ± antithymocyte globulin | 6 | 4 |
| Fludarabine, melphalan, antithymocyte globulin | 4 | 2 |
| TBI, melphalan | 1 | 0 |
| Fludarabine, thiotepa, melphalan | 1 | 0 |
| TBI, cyclophosphamide, thiotepa | 1 | 0 |
| Cyclosporin immunosuppression | 31 | 3 |
TBI = 12 Gy; cyclophosphamide = 2 × 60 mg/kg; thiotepa = 10 mg/kg; fludarabine = 5 × 30 mg/m2; antithymocyte globulin = 4 × 5 mg/kg.