Human Anti-BsmAb Immune Responses
| Patient no. | BsmAb (mg/m2) | HAHA (ng/mL) | HAMA (ng/mL) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Before RIT | 1–2 mo after RIT | 3 mo after RIT | 6 mo after RIT | Before RIT | 1–2 mo after RIT | 3 mo after RIT | 6 mo after RIT | ||
| 01-16 | 75 | 0 | 0 | 113 | ND | 1 | 0 | 0 | ND |
| 01-17 | 75 | 0 | 6 | 876 | 622 | 0 | 0 | 44 | 140 |
| 01-18 | 75 | 0 | 0 | ND | ND | 0 | 0 | ND | ND |
| 01-19 | 75 | 31 | 54 | ND | ND | 0 | 0 | ND | ND |
| 01-20 | 75 | 16 | 15 | 0 | ND | 0 | 0 | 0 | ND |
| 01-21 | 75 | 0 | 9 | 85 | 162 | 0 | 0 | 0 | 0 |
| 01-23 | 75 | 16 | 19 | 41 | ND | 0 | 0 | 0 | ND |
| 01-26 | 75 | 13 | 367 | 135 | ND | 0 | 0 | 0 | ND |
| 01-27 | 75 | 23 | 8 | 43 | ND | 0 | 0 | 0 | ND |
| 01-28 | 40 | 36 | 0 | ND | ND | 0 | 0 | ND | ND |
| 01-30 | 40 | 82 | 0 | ND | ND | 0 | 0 | ND | ND |
| 01-33 | 40 | ND | 0 | ND | ND | 0 | 0 | ND | ND |
ND = not done.
Positive result was >74 ng/mL for HAMA and >100 ng/mL for HAHA.