Functional Outcome in Patients With and Without Diabetes Mellitus According to Presence or Absence of Substantial Amount of Myocardial Viability on 18F-FDG SPECT
| Patient group | Clinical parameter | Before coronary revascularization | After coronary revascularization | P |
|---|---|---|---|---|
| Diabetes + viability + (n = 11) | CCS score | 2.7 ± 0.6 | 1.1 ± 0.3 | <0.0001 |
| NYHA class | 2.8 ± 1.0 | 2.1 ± 0.5 | <0.05 | |
| LVEF | 27 ± 9 | 31 ± 9 | <0.05 | |
| Diabetes + viability − (n = 18) | CCS score | 2.3 ± 0.9 | 1.4 ± 0.5 | 0.005 |
| NYHA class | 2.9 ± 1.0 | 2.8 ± 0.7 | NS | |
| LVEF | 35 ± 10 | 35 ± 9 | NS | |
| Diabetes − viability + (n = 40) | CCS score | 2.1 ± 1.1 | 1.4 ± 0.5 | <0.005 |
| NYHA class | 2.8 ± 1.0 | 2.1 ± 0.9 | <0.005 | |
| LVEF | 32 ± 10 | 35 ± 12 | 0.01 | |
| Diabetes − viability − (n = 40) | CCS score | 2.2 ± 1.0 | 1.4 ± 0.5 | <0.0001 |
| NYHA class | 2.2 ± 1.0 | 2.1 ± 0.9 | NS | |
| LVEF | 37 ± 10 | 38 ± 9 | NS |
Data are mean ± SD. CCS = Canadian Cardiovascular Society; NS = not statistically significant; NYHA = New York Heart Association; + = present; − = absent. A substantial amount of myocardial viability on 18F-FDG SPECT was defined as presence of ≥4 dysfunctional but viable segments.