Patient Characteristics, Tumor Localizations, and Tracer Uptake
| Patient no. | Age (y) | Sex | Tumor features | Primary site | Location of tumor lesions | Oct uptake | MIBG uptake |
|---|---|---|---|---|---|---|---|
| 1 | 72 | F | LGM, EC-type, F | Ileum | Liver (m), mesent LN (m), pulm (m), bone (m) | +++ (all; except bone ++/+++) | +++ (all; except bone ++/+++) |
| 2 | 73 | M | LGM, EC-type, F | Small bowel | Liver (m), primary (s) | +++ | +++ |
| 3 | 66 | F | LGM, EC-type, F | Ileum | Liver (m), mesent (s) | +++ | +++ |
| 4 | 55 | M | LGM, EC-type, F | Small bowel | Liver (m), mesent (s) | +++ | +++ (liver), + (mesent) |
| 5 | 67 | F | LGM, EC-type, F | Ileum | Liver (m) | +++ | +++ |
| 6 | 47 | F | LGM, EC-type, F | NK | Liver (3) | +++ | +++ |
| 7 | 53 | M | LGM, EC-type, F | Rectum | Liver (m) | +++ | +++ |
| 8 | 57 | M | LGM, EC-type, F | Ileum | Liver (m), mesent (m) | +++ (liver), ++/− (mesent) | +++ (liver), − (mesent) |
| 9 | 21 | M | LGM, EC-type, F | Ileum | Liver (m), inguinal LN (s) | +++ | — |
| 10 | 62 | M | LGM, NF | NK | Liver (m), bone (m) | +++ | +++ |
| 11 | 57 | F | LGM, EC-type, F | Ileum | Liver (2) | +++ | +++ |
| 12 | 34 | F | LGM, NF | NK | Liver (m), mesent (m), pancr (s) | +++ | +++ |
| 13 | 56 | F | LGM, NF | Ileum | Liver (m) | +++ | — |
| 14 | 43 | M | LGM, EC-type, F | Ileum | Liver (m) | +++ | +++ |
| 15 | 78 | F | LGM, EC-type, F | Ileum | Liver (m), bone (m) | +++ (liver), ++ (bone) | ++ (liver), +++ (bone) |
| 16 | 62 | M | LGM, EC-type, F | Small bowel | Liver (m), mesent (s) | +++ | +++ (liver), ++ (mesent) |
| 17 | 59 | M | LGM, EC-type, F | Colon | Liver (m), colon (s) | +++ | ++ (colon), − (liver) |
| 18 | 70 | M | LGM, NF | NK | Liver (m), bone (4) | +++ (liver), ++ (bone) | +++ (liver), ++ (bone) |
| 19 | 77 | M | LGM, EC-type, F | NK | Mesent (2) | +++ | +++ |
| 20 | 54 | F | LGM, NF | Jejunum | Mesent (2) | +++ | +++ |
| 21 | 65 | F | LGM, EC-type, F | Jejunum | Mesent (s) | ++ | — |
| 22 | 71 | M | LGM, NF | Ileum | Mesent (s) | +++ | +++ |
| 23 | 63 | M | LGM, NF | Small bowel | Abdom LN (2), large mesenteric mass (s) | +++ | +++ (mesent), ++ (abdom LN) |
| 24 | 75 | M | LGM, NF | Small bowel | Mesent (s) | ++ | + |
| 25 | 64 | M | LGM, NF | Jejunum | Mesent LN (2) | ++ | ++ |
| 26 | 60 | M | LGM, EC-type, F | Ileum | Bone (m) | +++/++ | — |
| 27 | 40 | F | LGM, EC-type, F | Bronchus | Mediast LN (s) | +++ | +++ |
| 28 | 52 | M | LGM, NF | Duodenum | Liver (m), mesent LN (s), primary tumor (s) | − (liver), ++ (LN), +++ (primary) | — |
| 29 | 62 | F | LGM, EC-type, F | Cecum | Liver (m) | +++ | +++ |
| 30 | 63 | M | LGM, EC-type, F | NK | Liver (2), mesent LN (s) | +++ (liver), ++ (LN) | +++ (liver), ++ (LN) |
| 31 | 61 | M | LGM, NF | Cecum | Liver (m) | +++ | + |
| 32 | 59 | F | HGM, NF | Rectum | Liver (m), mediast LN (m) | +++ (LN), − (liver) | — |
| 33 | 56 | M | LGM, NF | Rectum | Liver (m), pulm (s) | +++ | — |
| 34 | 79 | F | HGM, NF | Rectum | Liver (m) | ++/+++ | +/++ |
| 35 | 49 | M | LGM, NF | Rectum | Local recurrence (s), pelvic LN (m) | + (local retrop), − (LN) | + (local retrop), − (LN) |
| 36 | 60 | M | LGM, NF | Rectum | Liver (m), local (rectum) | +++ | — |
| 37 | 39 | F | HGM, NF | NK | Liver (m), bone (4) | +++ | — |
| 38 | 69 | M | HGM, NF | NK | Retrop pelvic and inguinal LN (m) | ++/+ (retrop, pelvic), ++ (inguinal) | — |
| 39 | 66 | F | HGM, NF | NK | Liver (s, large unresect), mesent LN (m), bone (s) | − (liver and LN), + (bone) | — |
| 40 | 62 | M | HGM, NF | Cecum | Liver (4), bone (m) | — | — |
| 41 | 62 | F | LGM, NF | Ileum | Liver (m), bowel prim (3) | +++ (liver), + (bone) | +++ (liver), + (bone) |
| 42 | 63 | M | LGM, sporadic ECL-type, NF | Stomach | Liver (m) | +++ | — |
| 43 | 62 | M | LGM, EC-type, F | Ileum | Liver (m), bone (3) | +++ (liver), ++/+++ (bone) | ++/+++ (liver), − (bone) |
| 44 | 66 | F | LGM, EC-type, F | NK | Liver (m), mesent LN (m), soft tissue (s) | +++ | +++ (liver), ++ (LN), + (soft tissue) |
| 45 | 60 | M | LGM, EC-type, F | Ileum | Liver (m) | +++ | +++ |
| 46 | 44 | F | LGM, NF | NK | Liver (m) | +++ | — |
| 47 | 40 | F | Unspec ICC, LGM, NF | Pancreas | Liver (m), pancr (s) | +++ | — |
| 48 | 54 | M | Gastrinoma, LGM, F | Pancreas | Liver (m), bone (m) | +++ | — |
| 49 | 44 | M | Gastrinoma, LGM, F | Pancreas | Liver (m), pancr (s) | +++ | +++/− (liver), − (pancr) |
| 50 | 64 | M | PPoma, HGM, NF | Pancreas | Liver (m), pancr (s) | ++/− (liver), + (pancr) | — |
| 51 | 63 | M | PPoma, LGM, F | Pancreas | Liver (3), pancr (s) | +++ | — |
| 52 | 59 | F | Insulinoma, LGM, F | Pancreas | Liver (m), pancr (s), mesent LN (m), mediastinal LN (2) | +++ | +++ |
| 53 | 25 | M | ICC, mixed exo-/ endocrine, LGM, NF | Pancreas | Liver(m), abdom LN (m), medias LN (m) | +++ | — |
| 54 | 71 | F | Unspec ICC, LGM, NF | Pancreas | Liver (m), bone (s), pancr (s) | +++ | — |
| 55 | 54 | F | Unspec ICC, LGM, NF | Pancreas | Liver (m) | +++ | — |
| 56 | 76 | M | Unspec ICC, LGM, NF | Pancreas | Liver (m), abdom LN (m), pancr (s) | +++ | − (all; except 1 liver metastases: +++) |
| 57 | 38 | F | Unspec ICC, LGM, NF | Pancreas | Liver (m) | +++ | — |
HGM = high-grade-malignant; LGM = low-grade-malignant; F = functioning; NF = nonfunctioning; ICC = islet cell carcinoma; NK = not known; s = single; m = multiple; pulm = pulmonary; mesent = mesenteric; LN = lymph node; pancr = pancreatic; abdom = abdominal; medias = mediastinal; retrop = retroperitoneal; unresect = unresected; prim = primary; unspec = unspecified; PPoma = pancreatic polypeptide-secreting tumor; tumoral tracer uptake: − = absent; + = clearly less than liver uptake; ++ = comparable to liver uptake; +++ = clearly more than liver uptake.