TABLE 2

Statistical Correlation Between Clinical Markers of Symptomatic HD Subjects and Fractional Brain Volumes

		Age-adjusted fGM		fWM		Age-adjusted fCSF
Clinical marker	n	S_r	P	S_r	P	S_r	P
Duration of disease (y)	47	NS		−0.54	<0.0001	0.47	0.0013
Stage (total functional capacity score)	47	0.31	0.035	0.46	0.0014	−0.52	<0.0001
Loss of total functional capacity units per year	36^*	−0.33	0.048		NS	0.37	<0.026