TABLE 2

MRI and ¹⁸F-FDG PET Data

	MRI		¹⁸F-FDG PET
Parameter	Control	FAD	Control	FAD
EC
Left	0.08 (0.07)	0.07 (0.05)	1.31 (0.22) [1.45 (0.18)]	1.02 (0.14) [1.14 (0.14)]^*
Right	0.09 (0.03)	0.07 (0.02)	1.23 (0.14) [1.30 (0.06)]	1.13 (0.14) [1.23 (0.05)]
Hip
Left	0.44 (0.09)	0.39 (0.05)	1.36 (0.06) [1.38 (0.06)]	1.22 (0.13) [1.24 (0.13)]^*
Right	0.58 (0.17)	0.43 (0.05)	1.32 (0.07) [1.33 (0.07)]	1.19 (0.14) [1.21 (0.15)]
IPL
Left	1.05 (0.11)	0.87 (0.21)^*	1.84 (0.31) [1.99 (0.25)]	1.56 (0.13) [1.67 (0.13)]^*
Right	1.08 (0.13)	0.88 (0.18)^†	1.87 (0.32) [1.99 (0.31)]	1.55 (0.12) [1.66 (0.12)]^*
PCC
Left	2.36 (0.61)	2.22 (0.43)	2.26 (0.23) [2.28 (0.23)]	1.75 (0.16) [1.83 (0.18)]^†
Right	2.38 (0.26)	2.19 (0.50)	2.18 (0.12) [2.22 (0.34)]	1.79 (0.19) [1.86 (0.18)]
STG
Left	3.47 (0.92)	3.39 (0.69)	1.64 (0.19) [1.76 (0.20)]	1.43 (0.13) [1.57 (0.16)]^*
Right	3.72 (0.65)	3.41 (0.40)	1.69 (0.18) [1.83 (0.21)]	1.47 (0.09) [1.62 (0.11)]^*
WB	4.82 (1.6)	3.71 (0.9)	1.66 (0.14) [1.78 (0.15)]	1.43 (0.12) [1.55 (0.13)]^*
Ventricular CSF (mL)	16.5 (5.7)	14.3 (4.4)	—	—
HS (cm³)	1,239 (94)	1,212 (114)	—	—
Pons MRglc	—	—	1,121 (427) [1,137 (439)]	1,239 (420) [1,245 (342)]

↵* P ≤ 0.05, FAD < control subjects.
↵† P ≤ 0.01, FAD < control subjects.
MRI measures = (ROI/HS volumes) × 100; ¹⁸F-FDG PET measures = ROI/pons MRglc; MRglc = glucose metabolism (overall count rate).
Values are means (SD) [atrophy-corrected MRglc values].