TABLE 1

Echocardiographic Measurements Before and Serially After Intramyocardial Ad.EGFP or Ad.EGFP.NIS Injection

	Ad.EGFP			Ad.EGFP.NIS
Measurement	Baseline	Day 4	Day 9	Baseline	Day 4	Day 9
Heart rate (bpm)	341 ± 40	328 ± 63	306 ± 42	300 ± 29	292 ± 33	318 ± 52
LV dimension
IVS thickness (mm)	1.5 ± 0.4	1.6 ± 0.3	1.7 ± 0.3	1.6 ± 0.4	1.8 ± 0.6	1.8 ± 0.3
PW thickness (mm)	1.8 ± 0.1	1.8 ± 0.2	1.7 ± 0.2	1.7 ± 0.3	1.6 ± 0.2	1.8 ± 0.3
Diastolic diameter (mm)	6.8 ± 0.6	6.8 ± 0.9	7.5 ± 1.0	6.9 ± 0.8	6.8 ± 0.6	7.5 ± 0.9
Systolic diameter (mm)	3.1 ± 0.8	3.7 ± 1.0	4.2 ± 0.7^*	3.1 ± 0.9	3.3 ± 0.8	4.4 ± 0.8^*
IVS/LVPW ratio	0.9 ± 0.1	0.9 ± 0.1	1.0 ± 0.2	1.0 ± 0.2	1.1 ± 0.3	1.0 ± 0.2
Diastolic volume (mL)	0.7 ± 0.2	0.7 ± 0.3	1.0 ± 0.3^†	0.7 ± 0.2	0.7 ± 0.2	1.0 ± 0.3^†
Systolic volume (mL)	0.1 ± 0.0	0.2 ± 0.1	0.2 ± 0.1^*	0.1 ± 0.1	0.1 ± 0.1	0.2 ± 0.1^†
LV mass (g)	0.7 ± 0.1	0.8 ± 0.2	0.9 ± 0.2^†	0.7 ± 0.1	0.8 ± 0.2	1.0 ± 0.2^‡
LV functional parameter
LV FS (%)	54.7 ± 10.0	46.7 ± 7.6^†	43.6 ± 4.9^‡	54.3 ± 9.1	48.6 ± 5.0	42.4 ± 4.7^*
LV EF (%)	88.2 ± 6.4	82.3 ± 7.7	79.6 ± 5.0^*	88.0 ± 5.4	86.5 ± 5.7	78.7 ± 4.6^*

↵* P < 0.005 compared with baseline measurements.
↵† P < 0.05 compared with baseline measurements.
↵‡ P < 0.01 compared with baseline measurements.
IVS = interventricular septum; PW = posterior wall; LVPW = LV posterior wall; LVFS = LV fractional shortening.
Data are mean ± SD.