TABLE 7

Comparison Between TdR Parameters Reported Previously and FLT in This Study

		TdR				FLT
Tissue	Region	Mean	Min	Max	n	Mean	Min	Max	n	% Δ
	Transport (K₁)
Tumor	NCE	0.018	0.005	0.028	13	0.005	0.003	0.007	3	−72
	CE	0.057	0.036	0.082	6	0.053	0.015	0.126	9	−7
	High	0.052	0.021	0.082	7	0.052	0.005	0.126	9	3
	Low	0.018	0.005	0.028	12	0.008	0.003	0.015	3	−8
C/L brain		0.020	0.007	0.051	24	0.004	0.003	0.006	12	−63
	Metabolic flux (K_TdR or K_FLT)
Tumor	NCE	0.011	0.005	0.016	13	0.001	0.001	0.002	3	−88
	CE	0.041	0.019	0.059	6	0.018	0.008	0.033	9	−55
	High	0.030	0.016	0.059	7	0.018	0.002	0.033	9	−39
	Low	0.011	0.005	0.016	12	0.003	0.001	0.008	3	−49
C/L brain		0.011	0.001	0.022	24	0.002	0.001	0.003	12	−82
Mean flux ratio for FLT/TdR in C/L brain					0.23
Mean flux ratio for FLT/TdR in high-grade gliomas					0.56

NCE = noncontrast-enhancing tumor; CE = contrast-enhancing tumor with MRI T1+Gd imaging; High = glioma grades III and IV; Low = glioma grade II; % Δ = percent difference in mean parameter value of TdR vs. FLT.