TABLE 6

Time to Peak Uptake (Minutes) in 6 Regions for 11C-MADAM (n = 9) and 11C-DASB (n = 6) (39)

Region11C-MADAM11C-DASB
3CM(1)3CM(2)2CM2CM
Raphe nuclei69.1 ± 16.370.1 ± 17.170.4 ± 18.271.3 ± 18.6
Putamen35.6 ± 6.1*35.7 ± 6.4†36.0 ± 6.6†46.0 ± 10.7
Hippocampal complex34.3 ± 4.7†34.3 ± 5.1†34.5 ± 5.0†42.5 ± 8.8
Cingulate cortex30.8 ± 6.031.1 ± 6.231.0 ± 6.235.2 ± 8.6
Frontal cortex‡26.6 ± 5.226.8 ± 5.426.8 ± 5.329.4 ± 6.9
Cerebellum24.2 ± 5.0na24.5 ± 5.029.3 ± 8.5

  • ↵* P < 0.1 (comparison with 11C-DASB data; 2-tailed t test.

  • ↵† P < 0.05.

  • ↵‡ 11C-DASB data represent dorsolateral prefrontal cortex.

  • na = not applicable.

    Data are presented as mean ± SD.