Circumstances Under Which Manual Correction of Automated VOI Positioning Was Considered Necessary from a Clinician’s Point of View and Number of Scans Affected
| Conditions | n |
|---|---|
| For manual correction of striatal VOI positioning | |
| Shift of single basal ganglia VOI of >2 mm | 0/155 |
| Brain too small compared with template with both basal ganglia VOIs being >4 mm too far apart (in most cases, resulting in shift of >2 mm on each side) | 2/155 |
| Rotational misalignment of >3° in any plane | 0/155 |
| For manual correction of occipital reference VOI positioning | |
| VOI shift resulting in overlap of any part of occipital reference region with either skull or ventricles of >4 mm | 6/155 |
| Rotational misalignment of >3° in any plane resulting in overlap of reference VOI with either skull or ventricles | 1/155 |