BP2 Values Calculated Using 5 Different Methods of Quantification
| Subject no. | Bolus/infusion experiments (120–180 min) | Bolus experiments | ||||||
|---|---|---|---|---|---|---|---|---|
| Reference tissue (0–180 min) | Logan analysis (0–180 min) | Peak equilibrium (40–80 min) | Transient equilibrium (90–180 min) | |||||
| 1 | 4.6 | 4.6 | 4.6 | 4.8 | 6.0 | |||
| 2 | 4.6 | 4.1 | 3.7 | 3.8 | 5.5 | |||
| 3 | 4.4 | 4.3 | 4.2 | 4.5 | 5.5 | |||
| 4 | 4.0 | 4.2 | 4.2 | 4.7 | 6.0 | |||
| 5 | 3.9 | 3.6 | 3.5 | 3.5 | 5.2 | |||
| Average ± SD | 4.3 ± 0.3 | 4.1 ± 0.4 | 4.0 ± 0.4 | 4.3 ± 0.6 | 5.6 ± 0.4 | |||
BP2 was calculated using Equation 2. Peak equilibrium and transient equilibrium were not calculated at tracer steady state.