BP1 Values Calculated Using 5 Different Methods of Quantification
| Subject no. | Bolus/infusion experiments (120–180 min) | Bolus experiments | ||||||
|---|---|---|---|---|---|---|---|---|
| Kinetic analysis (0–180 min) | Logan analysis (0–180 min) | Peak equilibrium (40–80 min) | Transient equilibrium (90–180 min) | |||||
| 1 | 22.9 | 21.8 | 20.4 | 26.4 | 31.5 | |||
| 2 | 20.7 | 19.8 | 18.3 | 31.7 | 34.0 | |||
| 3 | 20.6 | 20.9 | 19.2 | 26.0 | 34.0 | |||
| 4 | 21.3 | 20.7 | 18.1 | 30.9 | 41.1 | |||
| 5 | 19.6 | 22.6 | 18.2 | 24.4 | 39.0 | |||
| Average ± SD | 21.0 ± 1.2 | 21.1 ± 1.1 | 18.8 ± 1.0 | 27.9 ± 3.2 | 35.9 ± 4.0 | |||
BP1 was calculated using Equation 1. Peak equilibrium and transient equilibrium were not calculated at tracer steady state.