Subject no. | Bolus/infusion experiments | Bolus experiments | ||||||
---|---|---|---|---|---|---|---|---|
1 | −0.1 | −4.0 | 4.2 | 3.7 | 2.4–8.5 | |||
2 | 6.8* | 2.2 | −7.2* | 2.4 | 1.3–12.8 | |||
3 | −3.1 | −6.6 | −2.8 | 3.1 | 2.8–3.6 | |||
4 | 2.8 | 2.1 | −3.4 | 2.6 | 1.3–214.0 | |||
5 | −6.6 | −3.1 | −4.2 | 1.8 | 1.2–4.0 | |||
Average ± SD | −0.0 ± 5.2 | −1.9 ± 3.9 | −1.6 ± 4.9 | 2.7 ± 0.7 |
↵* Slope of regression line calculated from 120 to 240 min is significantly different from zero (P < 0.05). BP1, BP2, and plasma stability measures were calculated from bolus/infusion data. Individual bolus-to-infusion ratios and corresponding 95% confidence intervals were calculated from terminal clearance rate from plasma after bolus injection of 123I-PE2I.