TABLE 1

Patient Characteristics, Tumoral Tracer Uptake, and Proliferation Fraction (Ki-67 Index)

Patient no.Age (y)SexPathology findingTumor gradePretreatmentFLTFDGSurgery after PETKi-67 index (%)
SUVmaxT/N ratioSUVmaxT/N ratio
129FGlioblastomaIVGamma knife/RT/chemo0.973.644.880.52Yes10
265MGlioblastomaIVSurgery/RT/chemo1.694.886.241.04Yes5
363MGlioblastomaIVSurgery/RT/chemo1.385.126.872.31Yes25
456MGlioblastomaIVBiopsy only1.233.552.971.02Yes10
566MGlioblastomaIVSubtotal resection2.623.937.482.05Yes25
652MGlioblastomaIVSurgery/RT/chemo2.164.683.361.66Yes40
765MGlioblastomaIVBiopsy only1.154.517.371.40Yes40
873MGlioblastomaIVBiopsy/RT0.883.332.540.80Yes2
926MAnaplastic mixedIIIBiopsy/RT0.703.001.750.52Yes4
1031MGlioblastomaIVBiopsy only3.625.816.012.46Yes75
1140MGlioblastomaIVBiopsy only0.401.854.441.03No
1227FAnaplastic mixedIIISurgery/RT/chemo0.832.7016.02.89No
1358FGlioblastomaIVSurgery/RT/chemo1.023.485.951.45No
1437MGlioblastomaIVSurgery/RT/chemo1.433.624.900.90No
1560FGlioblastomaIVSurgery/RT/chemo1.143.283.200.76No
1659MGlioblastomaIVSurgery/RT/chemo1.072.647.471.18No
1745MAnaplastic oligodendrogliomaIIISurgery/ BCNU wafer*0.953.103.250.94No
1833FAstrocytomaIISurgery0.300.772.200.61Yes2
1959FOligodendrogliomaIISurgery0.271.024.470.81Yes2
2031MOligodendrogliomaIIBiopsy only0.421.032.771.04Yes3
2134FMixed gliomaIIBiopsy only0.251.103.200.88No
2251MGlioblastomaIVSurgery/RT/chemo0.351.072.410.47No
2344MAnaplastic mixedIIISurgery/RT/chemo0.271.061.361.14No
2465MAnaplastic oligodendrogliomaIIISurgery/RT/chemo0.220.932.160.41No
2524FAnaplastic oligodendrogliomaIIIBiopsy only1.271.953.430.83Yes10
  • * Patient had 1,3-bis-2-chloroethyl-1-nitrosourea (BCNU) wafer implanted at resection site during resective surgery.

  • Three patients had previously treated gliomas and had been off therapy and stable without clinical or MRI evidence of recurrent disease for >3 y.

  • SUVmax = maximum-pixel standardized uptake value; T/N ratio = ratio of mean uptake of voxels with top 20% SUVs to mean values of contralateral normal brain; RT = radiation therapy; chemo = chemotherapy.