TABLE 2

Comparison of Parameters During Exercise and Changes in Parameters Among 3 Groups

ParameterControl (n = 5)Group I (n = 12)Group II (n = 18)
Maximum workload (W)77 ± 2974 ± 2380 ± 33
Peak HR (bpm)119 ± 16125 ± 21129 ± 16
% increase in HR (%)75 ± 3570 ± 3973 ± 42
Peak MAP (mm Hg)126 ± 23120 ± 20131 ± 23
ΔMAP (mm Hg)28 ± 1026 ± 1726 ± 13
Peak LVEDP (mm Hg)15.4 ± 4.028.0 ± 7.7*26.0 ± 10.4*
ΔLVEDP (mm Hg)8.0 ± 4.112.1 ± 4.8*11.2 ± 4.8
Peak LV dP/dtmax (mm Hg/s)3,970 ± 4042,205 ± 662*†3,127 ± 851
% increase in LV dP/dtmax (%)89 ± 3132 ± 15*†80 ± 37
Peak T1/2 (ms)24 ± 4.435 ± 10.1*†25 ± 7.1
% shortening in T1/2 (%)−37 ± 6.9−17 ± 7.8*†−40 ± 14.5
Peak CI (L/min · m2)6.4 ± 1.26.3 ± 0.86.4 ± 0.6
% increase in CI (%)146 ± 42125 ± 49113 ± 41
Peak PAWP (mm Hg)16.1 ± 4.029.9 ± 7.6*26.5 ± 6.6*
ΔPAWP (mm Hg)10.0 ± 2.915.2 ± 5.2*14.4 ± 5.1*

  • ↵* P < 0.05 vs. control group.

  • ↵† P < 0.05 vs. group II.

  • % = percentage change in parameter from rest to exercise; Δ = absolute change in parameter from rest to exercise.

    Data are expressed as mean ± SD.