TABLE 3

Radiation Dosimetry: 177Lu-J591 vs. 90Y-J591

OrganRadiation dosimetry (cGy/mCi)
177Lu-DOTA-J59190Y-DOTA-J591
Liver7.77 ± 2.2324.39 ± 8.39
Spleen7.28 ± 3.4118.22 ± 6.14
Kidneys5.20 ± 1.2916.55 ± 4.00
Heart wall3.50 ± 0.7011.07 ± 2.24
Lungs2.79 ± 0.8010.63 ± 2.62
Red marrow1.17 ± 0.373.37 ± 1.59
Bone surfaces0.70 ± 0.142.53 ± 0.97
Urinary bladder wall0.97 ± 0.222.63 ± 1.09
Muscle0.42 ± 0.071.08 ± 0.28
Testes0.36 ± 0.131.08 ± 0.28
Total body0.71 ± 0.102.05 ± 0.31
Effective dose equiv.2.14 ± 0.356.60 ± 0.94
Effective dose1.33 ± 0.194.19 ± 0.51
  • Equiv. = equivalent.