TABLE 1

Mean Dosages of Amisulpride and Background-Corrected D2 Receptor Binding

Patient no.Dosage of amisulpride (mg/d)Dosage of amisulpride (mg/kg of body weight/d)Plasma concentration of amisulpride (μg/L)D2 receptor occupancy* (%)
1500.817741.9
21001.552750.1
31001.7412860.3
41501.7012058.3
52002.6710875.9
62002.9510465.5
73003.2867.6
83003.798466.5
93003.8014578.9
103004.0611871.9
113004.145568.6
123004.1731282.9
133004.258265.0
143005.1738585.9
154004.658851.3
164005.0117981.7
174005.7018477.0
185006.7542181.7
195008.6511479.5
206006.3217792.1
216008.0512166.1
226009.6921979.4
238006.5816977.8
248008.516487.8
2580010.1322360.6
2680010.6126387.4
2780010.81518100.0
2880011.5126170.5
291,20019.2091093.4
  • * (SBcontrol − SBpatient)/SBcontrol.