Stress Studies: Comparison of SPECT 99mTc-MIBI Uptake with 13N-Ammonia PET Perfusion (n = 23)
Segment | PET | SPECT NC | SPECT AC | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Flow (mL/100 mL · min) | % | NC | MD* | P* | AC | MD† | P† | ||||||
Anteroapical | 195.6 ± 56.9 | 67.9 ± 12.0 | 88.7 ± 10.5 | 20.8 | <0.0001 | 80.6 ± 8.8 | 12.7 | <0.0001 | |||||
Inferoapical | 191.0 ± 59.9 | 65.0 ± 12.8 | 83.3 ± 9.8 | 18.6 | <0.0001 | 81.8 ± 7.8 | 17.1 | <0.0001 | |||||
Apical anterolateral | 213.6 ± 75.0 | 73.8 ± 14.1 | 94.0 ± 6.0 | 20.3 | <0.0001 | 89.2 ± 8.9 | 15.4 | <0.0001 | |||||
Apical anterior | 207.0 ± 58.3 | 72.0 ± 12.0 | 90.5 ± 9.4 | 18.5 | <0.0001 | 81.8 ± 9.5 | 9.8 | 0.0011 | |||||
Apical anteroseptal | 218.0 ± 69.4 | 75.4 ± 14.6 | 88.6 ± 8.1 | 13.1 | 0.0001 | 87.6 ± 9.3 | 11.9 | 0.0007 | |||||
Apical inferoseptal | 219.3 ± 96.1 | 78.1 ± 16.1 | 89.0 ± 9.7 | 11.0 | NS | 95.0 ± 7.5 | 15.6 | 0.0041 | |||||
Apical inferior | 215.6 ± 76.6 | 77.2 ± 16.5 | 78.9 ± 11.0 | −1.0 | NS | 87.7 ± 8.4 | 8.0 | 0.0406 | |||||
Apical inferolateral | 212.9 ± 73.4 | 73.1 ± 12.3 | 83.2 ± 8.2 | 10.1 | 0.0001 | 86.4 ± 8.2 | 13.3 | <0.0001 | |||||
Mid anterolateral | 223.5 ± 69.6 | 78.2 ± 14.7 | 92.4 ± 9.9 | 14.2 | <0.0001 | 90.1 ± 10.9 | 11.9 | 0.0002 | |||||
Mid anterior | 208.4 ± 70.1 | 73.2 ± 14.1 | 88.3 ± 6.7 | 15.6 | <0.0001 | 85.7 ± 8.8 | 13.1 | 0.0003 | |||||
Mid anteroseptal | 221.7 ± 77.3 | 80.6 ± 11.9 | 84.9 ± 9.0 | 4.1 | NS | 88.9 ± 8.5 | 8.3 | 0.0358 | |||||
Mid inferoseptal | 257.6 ± 140.9 | 77.7 ± 19.1 | 79.7 ± 10.1 | 2.2 | NS | 90.4 ± 8.3 | 12.7 | 0.0305 | |||||
Mid inferior | 255.1 ± 99.1 | 84.4 ± 12.7 | 72.7 ± 12.0 | −10.6 | 0.0022 | 86.9 ± 10.7 | 3.6 | NS | |||||
Mid inferolateral | 239.1 ± 86.8 | 82.0 ± 13.5 | 78.6 ± 10.7 | −3.2 | NS | 86.2 ± 11.7 | 5.4 | NS | |||||
Basal anterolateral | 222.3 ± 77.2 | 76.9 ± 15.1 | 81.7 ± 10.5 | 4.7 | NS | 82.4 ± 10.2 | 5.4 | 0.0421 | |||||
Basal anterior | 221.1 ± 85.2 | 74.8 ± 14.5 | 77.1 ± 8.5 | 1.8 | NS | 79.4 ± 7.6 | 4.4 | NS | |||||
Basal anteroseptal | 200.6 ± 75.1 | 64.4 ± 13.3 | 62.6 ± 11.3 | 3.9 | NS | 65.8 ± 10.2 | 5.3 | NS | |||||
Basal inferoseptal | 216.4 ± 102.8 | 64.4 ± 17.6 | 57.8 ± 10.1 | −1.9 | NS | 68.1 ± 9.7 | 6.5 | NS | |||||
Basal inferior | 245.9 ± 117.0 | 77.1 ± 23.8 | 64.0 ± 11.7 | −12.9 | 0.0156 | 79.0 ± 12.0 | 1.0 | NS | |||||
Basal inferolateral | 191.1 ± 59.9 | 80.0 ± 13.4 | 71.2 ± 12.7 | −9.1 | 0.0314 | 79.1 ± 12.9 | −1.0 | NS |
↵* Comparison of PET and NC.
↵† Comparison of PET and AC.
NC = nonattenuation-corrected SPECT stress study; AC = attenuation-corrected SPECT stress study; % = studies normalized to segment with maximum flow (PET) or uptake (SPECT); MD = mean difference; NS = not significant.
Data are given as mean of 23 studies ± SD.